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Hantaflow
Old World hantavirus

Hantaan virus

Hantaan virus is the prototype of the genus and causes the most severe form of HFRS. It was identified after Korean War-era outbreaks among soldiers near the Hantan River.

Profile

  • Short name: HTNV
  • Family: Old World
  • Reservoir: Striped field mouse (Apodemus agrarius)
  • Primary region: South Korea, China, Russia (Far East)
  • Causes: Hemorrhagic Fever with Renal Syndrome (HFRS)
  • Case-fatality rate: ~5–15% (HFRS, severe form)
  • Person-to-person transmission: Not documented
  • Identified: 1978

Key facts

  • Reservoir: striped field mouse (Apodemus agrarius).
  • Causes severe HFRS with high renal involvement.
  • Endemic in eastern China, the Korean peninsula, and Russian Far East.
  • Hantavac and Hantavax vaccines target Hantaan-family viruses (used in Korea, China).

Sources for the above: Lee, Lee & Johnson, J Infect Dis 1978 (initial Hantaan virus isolation) · Lee SH et al., J Korean Med Sci 2013 (HFRS epidemiology, Korea 2001–2010) · Wen et al., One Health 2024 (16-year national HFRS surveillance, China)

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