Profile
- Short name: HTNV
- Family: Old World
- Reservoir: Striped field mouse (Apodemus agrarius)
- Primary region: South Korea, China, Russia (Far East)
- Causes: Hemorrhagic Fever with Renal Syndrome (HFRS)
- Case-fatality rate: ~5–15% (HFRS, severe form)
- Person-to-person transmission: Not documented
- Identified: 1978
Key facts
- Reservoir: striped field mouse (Apodemus agrarius).
- Causes severe HFRS with high renal involvement.
- Endemic in eastern China, the Korean peninsula, and Russian Far East.
- Hantavac and Hantavax vaccines target Hantaan-family viruses (used in Korea, China).
Sources for the above: Lee, Lee & Johnson, J Infect Dis 1978 (initial Hantaan virus isolation) · Lee SH et al., J Korean Med Sci 2013 (HFRS epidemiology, Korea 2001–2010) · Wen et al., One Health 2024 (16-year national HFRS surveillance, China)